Home-based prehabilitation improved 6-minute walk distance before surgery in prefrail/frail men: RCT.
A randomized controlled trial of 80 prefrail and frail men aged ≥60 undergoing radical prostatectomy compared short-term home-based multimodal prehabilitation (exercise, nutrition, psychology, pelvic floor training, breathing, health guidance) to usual care alone over a median 12-day preoperative period. The prehabilitation group improved 6-minute walk distance by 27.70 m from baseline to preoperatively, while usual care declined by 3.12 m, yielding a 30.82 m between-group difference (P < 0.001). Exploratory findings suggested faster early ambulation, gastrointestinal recovery, and shorter hospital stay.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Jul 24, 2026 · Discovered: Sep 15, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- 80
- Duration
- —
- Population
- Men aged 60 or older with prostate cancer classified as prefrail or frail, scheduled for elective radical prostatectomy
- Primary outcome
- Functional capacity measured by 6-min walk test (6MWT) change from baseline to day before surgery
- Effect size
- Between-group difference in 6MWT change: 30.82 m (95% CI, 25.32 to 36.33; P < 0.001). Prehabilitation group: 27.70 ± 16.86 m improvement; usual care group: -3.12 ± 3.62 m change
- Significance
- Significant
- Journal
- BMC Geriatrics
- Published
- Jul 24, 2026
Sources
Primary source
- BMC geriatrics ↗Peer reviewed
Assessment history
9/23/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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