Assessment superseded
Klotho gene therapy safety and efficacy tested in healthy adults without control group.
An interventional pilot study investigated safety and efficacy of injectable Klotho plasmid gene therapy in healthy adult volunteers. The study was non-placebo-controlled. Sample size and effect size were not reported in the available information.
OBSERVATIONALMinor significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Aug 27, 2026 · Discovered: Sep 15, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Observational
- Sample size
- —
- Duration
- —
- Population
- Healthy adult volunteers
- Primary outcome
- Safety and efficacy of Klotho gene therapy
- Effect size
- —
- Significance
- Not reported
- Journal
- Minicircle
- Published
- Aug 27, 2026
Sources
Primary source
- Minicircle ↗Clinical trial
Source versions
Assessment history
9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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