Assessment superseded
Targeting Muscle-Bone Crosstalk: The Potential of Physical Therapy in Managing Cancer-Induced Cachexia
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
RCTMinor significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Sep 8, 2026 · Discovered: Sep 17, 2026 · Assessed: — · Research update
What it does not prove
- The abstract reports aims and methods only; no actual results, effect sizes, or statistical comparisons are provided, so efficacy of the intervention cannot be determined from this material
- Sample size is not reported, limiting assessment of statistical power and generalizability
- This describes a study design and rationale rather than completed research findings
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- 3 months
- Population
- Non-metastatic cancer patients aged 40–60 undergoing neoadjuvant chemotherapy
- Primary outcome
- Changes in biomarker levels (myokines and osteokines) and functional physical outcomes
- Effect size
- —
- Significance
- Not reported
- Journal
- Pharos University in Alexandria
- Published
- Sep 8, 2026
Sources
Primary source
- Pharos University in Alexandria ↗Clinical trial
Recorded source passages
Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.
This is a randomized controlled trial (RCT), patients aged 40 to 60 receiving neoadjuvant chemotherapy are assigned to either a control group receiving standard chemotherapy and nutritional counseling, or an experimental group receiving a progressive 3-month exercise program (combining aerobic treadmill training and resistance exercises) alongside standard care.
The study aims to evaluate changes in biomarker levels (such as myokines and osteokines) and functional physical outcomes to determine whether targeted exercise can effectively attenuate cachexia and improve rehabilitation outcomes prior to surgery
Source versions
Assessment history
9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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