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  1. Trial registry · no verified findings· Santen Inc.

    A Phase 2, Randomized, Masked, Controlled Clinical Study to Assess the Safety and Efficacy of Lucentis® Plus Sirolimus Versus Lucentis® Plus Placebo in Patients With Sub-Foveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

    Published Jan 10, 2013Added 1moStart a discussionShare on XRapamycin

    Trial registry update: TERMINATED. No results reported in the supplied registry record.

    Evidence assessment pending · RCT

    Read the source · Santen Inc. ↗
  2. Trial registry · no verified findings· Santen Inc.

    A Phase 1/2, Randomized Clinical Study to Assess the Safety and Efficacy of Sirolimus in Patients With Newly Diagnosed, Treatment-Naive Sub-Foveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

    Published Jan 10, 2013Added 1moStart a discussionShare on XRapamycin

    Trial registry update: TERMINATED. No results reported in the supplied registry record.

    Evidence assessment pending · RCT

    Read the source · Santen Inc. ↗
  3. Trial registry · no verified findings· Novartis Pharmaceuticals

    RCT of oral everolimus alone or with lucentis for neovascular age-related macular degeneration; results not reported

    Published Aug 19, 2011Added 1moStart a discussionShare on XRapamycin

    A randomised, double-masked, parallel group study designed to assess the safety and efficacy of oral everolimus (an mTOR inhibitor in the rapamycin class) alone or combined with lucentis in patients with neovascular age-related macular degeneration. No efficacy or safety results were reported in the material provided.

    Evidence assessment pending · RCT

    Read the source · Novartis Pharmaceuticals ↗