Abolere mortem

What actually changed in longevity science

Research worth understanding. News worth reading. A clearer view of living longer.

Longevity landscape

85.7years

Modeled age at death · +2.3 vs reference

Research comparison across study populations—not a personal forecast.

Click a line to see the exact studies that calculate it. Use the tags in the feed to add or remove evidence.

4 selected source groups · 50% effect transfer. Sources include different study populations; their combined effect has not been tested as a treatment package.

Starting ageUS life table

Model assumptions

Include observational evidenceReported benefit carried into modelAdditional overlapping benefitsAssumed effect duration

Effect transfer and overlap are sensitivity assumptions, not measured correction factors. Age and sex change the reference life table; they do not establish treatment eligibility. Shading shows source bounds, not a combined confidence interval.

Nonfatal harms, adherence and treatment interactions are not modeled. Model longevity-scenarios-1.

Methodology & limitations →

What matters now

Important findings, useful explanations, and setbacks worth knowing about.

All stories →

3 stories from the past 72 hours. Older stories keep their original dates. Ranking reflects relevance, recency and reader interest—not proof of benefit.

Longevity news

News, research and the studies that currently shape the longevity chart—all in one stream.

Trial registry · no verified findings· City of Hope Medical Center
The Effect of Exercise and Nicotinamide Riboside on Muscle Health and Insulin Resistance in Adult Survivors of Childhood Cancer With Prediabetes: A Pilot Feasibility Study
Published Oct 23, 2026Added 2dStart a discussion Share on X Exercise Nicotinamide riboside
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · City of Hope Medical Center ↗
Trial registry · no verified findings· Odense University Hospital
SENolytics to Improve Osteoporosis Therapy: a Randomised Controlled Clinical Trial The SENIOR Trial
Published Oct 23, 2026Added 2dStart a discussion Share on X Senolytics
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Odense University Hospital ↗
Trial registry · no verified findings· Ahmed Adel Ahmed Elsayed Ali Radwan
Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia
Published Oct 21, 2026Added 4dStart a discussion Share on X Resistance training
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Ahmed Adel Ahmed Elsayed Ali Radwan ↗
Research affecting the chart· PubMed
Combined lifestyle factors, all-cause mortality and cardiovascular disease
Published 2020Observational researchGeneral adult evidence
Directly changes the Combined lifestyle chart input
74 studies; 2,584,766 participants in the all-cause mortality analysis.
Study scope and limits
Adults in prospective cohorts; populations and lifestyle definitions varied.
Healthiest versus least-healthy combinations of smoking, activity, diet, weight and alcohol factors.
Observational association, with residual confounding and heterogeneous lifestyle scores. Not the effect of changing an average person’s habits. Alcohol in the score is not a recommendation to drink.
Read the study · PubMed ↗
Trial registry · no verified findings· Universidade Cesumar (UNICESUMAR)
Interdisciplinary Approaches to Managing Excess Weight and Promoting Health in Older Adults: a Multimodal Intervention
Published Oct 20, 2026Added 5dStart a discussion Share on X Resistance training
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Universidade Cesumar (UNICESUMAR) ↗
Trial registry · no verified findings· Universidad de Granada
Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.
Published Oct 23, 2026Added 2dStart a discussion Share on X Exercise
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · OBSERVATIONAL
Read the source · Universidad de Granada ↗
Research affecting the chart· PubMed
Associations Between Exercise Training, Physical Activity, Sedentary Behaviour and Mortality
Published 2025Observational researchGeneral adult evidence
Directly changes the Physical activity chart input
Umbrella review of meta-analyses; equivalent hazard ratio for leisure-time physical activity.
Study scope and limits
Adults in the self-reported leisure-time physical activity syntheses.
Higher versus lower self-reported leisure-time physical activity; contrasts vary across studies.
Authors classify the association as suggestive evidence. Self-report, residual confounding and overlapping reviews limit interpretation. Replaces the combined lifestyle estimate rather than stacking on it.
Read the study · PubMed ↗
Trial registry · no verified findings· Capital Medical University
Development and Evaluation of a Muscle Health Exercise Program On Sarcopenia In Breast Cancer Survivors During Rehabilitation
Published Oct 19, 2026Added 6dStart a discussion Share on X Resistance training
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Capital Medical University ↗
Trial registry · no verified findings· University of Salamanca
Effectiveness of a Combined Strength Training and Progressive Muscle Relaxation Program in Reducing Frailty in Informal Caregivers of People With Alzheimer's Disease: A Randomized Controlled Trial
Published Oct 16, 2026Added 9dStart a discussion Share on X Resistance training
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · University of Salamanca ↗
Research affecting the chart· PubMed
Efficacy and safety of more intensive lowering of LDL cholesterol
Published 2010Randomized researchCardiovascular prevention trial populations
Directly changes the Statins chart input
CTT individual participant meta-analysis of 26 trials; about 170,000 participants overall.
Study scope and limits
Participants enrolled in randomized LDL-lowering trials, with varied cardiovascular risk.
Per 1 mmol/L lower LDL cholesterol, across statin versus control and more- versus less-intensive regimens.
Mortality rate ratio is treated as a proportional hazard multiplier in this model. Trial populations and LDL changes differ; not a longevity estimate for healthy people or a prescribing recommendation.
Read the study · PubMed ↗
Trial registry · no verified findings· Centenario Hospital Miguel Hidalgo
Effect of Egg Albumin and Agave Fructan Supplementation Combined With Functional Exercise on Muscle Mass, Physical Function, and Inflammatory Status in Patients Receiving Hemodialysis: A Randomized Controlled Trial
Published Oct 16, 2026Added 9dStart a discussion Share on X Exercise
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Centenario Hospital Miguel Hidalgo ↗
Trial registry · no verified findings· Cedars-Sinai Medical Center
A PHASE II, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE ONGOING LUNG DECLINE WITH AGE INTENSIFIED RESPONSE (OLD AIR)
Published Oct 15, 2026Added 10dStart a discussion Share on X Senolytics
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · Cedars-Sinai Medical Center ↗
Research affecting the chart· PubMed
Cardiovascular and Kidney Outcomes and Mortality With Long-Acting GLP-1 Receptor Agonists
Published 2025Randomized researchType 2 diabetes trial populations
Directly changes the GLP-1 agonists chart input
10 randomized trials; 71,351 participants.
Study scope and limits
People with type 2 diabetes in large cardiovascular and kidney outcome trials.
Long-acting GLP-1 receptor agonist versus placebo, on top of trial background care.
Class-level synthesis in type 2 diabetes; not transferable to healthy adults, every agent, or lifelong use. Trials already include other care, so combining effects can double-count benefit.
Read the study · PubMed ↗
Trial registry · no verified findings· University of Illinois at Chicago
Training the Aging Brain Through Speed: Examining Cerebrovascular Adaptations Associated With Motor-Cognitive Performance Following High-Velocity Resistance Training in Older Adults at Risk for AD/ADRD
Published Oct 14, 2026Added 11dStart a discussion Share on X Resistance training
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending · RCT
Read the source · University of Illinois at Chicago ↗
Research affecting the chart· journals.plos.org
SGLT2 inhibitors in patients with chronic kidney disease with or without type 2 diabetes
Published 2023Randomized researchChronic kidney disease trial populations
Directly changes the SGLT2 inhibitors chart input
Systematic review of 14 randomized trials; all-cause mortality is a secondary endpoint.
Study scope and limits
People with chronic kidney disease, with or without type 2 diabetes.
SGLT2 inhibitor plus standard therapy versus placebo or standard therapy.
The 14 trials cover the review as a whole, not necessarily this endpoint. Kidney disease populations differ from the reference life table. Background treatment overlaps with other selections.
Read the study · journals.plos.org ↗

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Epigenetic clocks →Metformin →Senolytics →Smoking cessation →Exercise →SGLT2 inhibitors →Klotho →Air quality →