Interventions
Where each approach stands and the latest research in our collection. Every overview links to its background sources and recent updates; detailed AI reviews are available where completed.
40 tracked topics · AI-written overviews, not expert-reviewed · Recent updates cover the last 30 days.
- Air quality
Behavioral · 0 collected reports
Fine-particle air pollution contributes to cardiovascular and respiratory disease and premature death. Reducing exposure is therefore a health-protection issue with substantial population-level evidence. The benefit of a specific personal measure, such as a device or a change in routine, still depends on actual exposure reduction and should not be inferred solely from a general pollution statistic. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Alcohol reduction
Behavioral · 1 collected reports
Alcohol contributes to several cancers and other serious health problems, and drinking less reduces exposure to those risks. The current public-health case is harm reduction, not using alcohol as a longevity tool. Older associations between moderate drinking and better health should not be read as proof that starting to drink improves health or lengthens life. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Caloric restriction
Behavioral · 2 collected reports
Reducing calorie intake without malnutrition has produced ageing-related effects in animals and improvements in some human disease-risk markers. Human studies such as CALERIE also highlight tradeoffs, including losses of bone or lean tissue. Changes in blood pressure, metabolism or ageing markers are not themselves proof of longer human life; nutrition and long-term outcomes remain central questions. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Exercise
Behavioral · 75 collected reports
Regular physical activity has established benefits for heart health, physical function and independence as people age. The practical evidence covers aerobic activity, strength and balance, rather than one special longevity workout. Better function and lower disease risk are meaningful outcomes; they do not translate into a guaranteed number of extra years for an individual. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research → - Intermittent fasting
Behavioral · 2 collected reports
Intermittent fasting changes when people eat, and may also reduce how much they eat. Human research has examined weight and metabolic or ageing-related markers, but those outcomes should not be confused with demonstrated life extension. An important question is whether meal timing adds benefit beyond changes in total food intake, and whether an approach remains appropriate over time. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Mediterranean diet
Behavioral · 6 collected reports
A Mediterranean-style diet emphasizes plant foods, olive oil and foods such as nuts and fish. The reanalysed PREDIMED trial found fewer major cardiovascular events in high-risk adults assigned to versions supplemented with olive oil or nuts. That supports cardiovascular prevention in the population studied, rather than proving that one diet reverses ageing or guarantees longer life. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 5, 2026: “Study and Design of New Sustainable Exercise and Dietary-nutritional Programs for the Treatment of Metabolic Disorders in Elderly Women”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research → - Protein restriction
Behavioral · 2 collected reports
Reducing protein is not a simple healthy-ageing rule. Protein is needed to maintain muscle, and older adults can respond less strongly to a given amount of dietary protein. Research on nutrient signalling must therefore be balanced against physical function and muscle loss; a proposed ageing mechanism does not establish that eating less protein benefits an older person. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Resistance training
Behavioral · 55 collected reports
Strength training helps maintain muscle, physical function and the ability to manage everyday tasks with age. These are useful health benefits in their own right, especially when combined with aerobic and balance activity. The clearest case is preserving function and independence; a change in muscle strength alone does not measure life extension. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research → - Sleep
Behavioral · 3 collected reports
Sleep supports mental and physical health, alertness and day-to-day function. Persistent poor sleep can also signal a treatable condition such as sleep apnea, rather than simply normal ageing. The useful distinction is between improving sleep health and claiming that a particular sleep duration or product will extend lifespan. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research → - Smoking cessation
Behavioral · 2 collected reports
Stopping smoking is an established way to reduce premature death and risks of heart disease, cancer and lung disease. Benefits occur at any age, including for people who have smoked for many years. This is a direct prevention opportunity with health-outcome evidence, although the size and timing of benefit vary with a person’s smoking history and health. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged.
AI review not yet available
Explore research → - Social connection
Behavioral · 5 collected reports
Loneliness and social isolation are associated with poorer physical and mental health, including heart disease and cognitive decline. Social relationships therefore matter for healthy ageing and quality of life. Much of the risk evidence is observational, so an association cannot tell us precisely how much a particular social activity would change someone’s lifespan. Source ↗ Recently: The latest trial-registry update in our collection is dated Sep 30, 2026: “Immersive Group Dance in Virtual Reality Improves Perceived Social Cohesion in Older Adults: A Technology-Assisted Movement Intervention - A Two-Arm, Parallel-Group Randomized Controlled Trial With Sex-Based Comparison”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research → - VO2 max training
Behavioral · 6 collected reports
Aerobic training improves the ability to sustain activity and is part of an established approach to healthy ageing. VO₂ max describes how much oxygen the body can use during intense exercise. It is a fitness measure, not a lifespan clock: improving a test result should not automatically be interpreted as gaining a particular number of years. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 26, 2026: “Effect of Preoperative Resistance and Aerobic Endurance Training on Surgical Outcomes and Evaluation of Patient Compliance With Prehabilitation in Colorectal Surgery: A Randomized Controlled Trial”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI review not yet available
Explore research →
| Intervention | Current state & recent changes | Research & review |
|---|---|---|
| Air quality Behavioral | Fine-particle air pollution contributes to cardiovascular and respiratory disease and premature death. Reducing exposure is therefore a health-protection issue with substantial population-level evidence. The benefit of a specific personal measure, such as a device or a change in routine, still depends on actual exposure reduction and should not be inferred solely from a general pollution statistic. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 0 collected reports AI review not yet available |
| Alcohol reduction Behavioral | Alcohol contributes to several cancers and other serious health problems, and drinking less reduces exposure to those risks. The current public-health case is harm reduction, not using alcohol as a longevity tool. Older associations between moderate drinking and better health should not be read as proof that starting to drink improves health or lengthens life. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 1 collected reports AI review not yet available |
| Caloric restriction Behavioral | Reducing calorie intake without malnutrition has produced ageing-related effects in animals and improvements in some human disease-risk markers. Human studies such as CALERIE also highlight tradeoffs, including losses of bone or lean tissue. Changes in blood pressure, metabolism or ageing markers are not themselves proof of longer human life; nutrition and long-term outcomes remain central questions. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 2 collected reports AI review not yet available |
| Exercise Behavioral | Regular physical activity has established benefits for heart health, physical function and independence as people age. The practical evidence covers aerobic activity, strength and balance, rather than one special longevity workout. Better function and lower disease risk are meaningful outcomes; they do not translate into a guaranteed number of extra years for an individual. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 75 collected reports AI review not yet available |
| Intermittent fasting Behavioral | Intermittent fasting changes when people eat, and may also reduce how much they eat. Human research has examined weight and metabolic or ageing-related markers, but those outcomes should not be confused with demonstrated life extension. An important question is whether meal timing adds benefit beyond changes in total food intake, and whether an approach remains appropriate over time. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 2 collected reports AI review not yet available |
| Mediterranean diet Behavioral | A Mediterranean-style diet emphasizes plant foods, olive oil and foods such as nuts and fish. The reanalysed PREDIMED trial found fewer major cardiovascular events in high-risk adults assigned to versions supplemented with olive oil or nuts. That supports cardiovascular prevention in the population studied, rather than proving that one diet reverses ageing or guarantees longer life. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 5, 2026: “Study and Design of New Sustainable Exercise and Dietary-nutritional Programs for the Treatment of Metabolic Disorders in Elderly Women”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 6 collected reports AI review not yet available |
| Protein restriction Behavioral | Reducing protein is not a simple healthy-ageing rule. Protein is needed to maintain muscle, and older adults can respond less strongly to a given amount of dietary protein. Research on nutrient signalling must therefore be balanced against physical function and muscle loss; a proposed ageing mechanism does not establish that eating less protein benefits an older person. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 2 collected reports AI review not yet available |
| Resistance training Behavioral | Strength training helps maintain muscle, physical function and the ability to manage everyday tasks with age. These are useful health benefits in their own right, especially when combined with aerobic and balance activity. The clearest case is preserving function and independence; a change in muscle strength alone does not measure life extension. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 55 collected reports AI review not yet available |
| Sleep Behavioral | Sleep supports mental and physical health, alertness and day-to-day function. Persistent poor sleep can also signal a treatable condition such as sleep apnea, rather than simply normal ageing. The useful distinction is between improving sleep health and claiming that a particular sleep duration or product will extend lifespan. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 3 collected reports AI review not yet available |
| Smoking cessation Behavioral | Stopping smoking is an established way to reduce premature death and risks of heart disease, cancer and lung disease. Benefits occur at any age, including for people who have smoked for many years. This is a direct prevention opportunity with health-outcome evidence, although the size and timing of benefit vary with a person’s smoking history and health. Source ↗ Recently: No update dated within the past 30 days is recorded in our collection. This describes our coverage, not a conclusion that the wider research is unchanged. Explore research → | 2 collected reports AI review not yet available |
| Social connection Behavioral | Loneliness and social isolation are associated with poorer physical and mental health, including heart disease and cognitive decline. Social relationships therefore matter for healthy ageing and quality of life. Much of the risk evidence is observational, so an association cannot tell us precisely how much a particular social activity would change someone’s lifespan. Source ↗ Recently: The latest trial-registry update in our collection is dated Sep 30, 2026: “Immersive Group Dance in Virtual Reality Improves Perceived Social Cohesion in Older Adults: A Technology-Assisted Movement Intervention - A Two-Arm, Parallel-Group Randomized Controlled Trial With Sex-Based Comparison”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 5 collected reports AI review not yet available |
| VO2 max training Behavioral | Aerobic training improves the ability to sustain activity and is part of an established approach to healthy ageing. VO₂ max describes how much oxygen the body can use during intense exercise. It is a fitness measure, not a lifespan clock: improving a test result should not automatically be interpreted as gaining a particular number of years. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 26, 2026: “Effect of Preoperative Resistance and Aerobic Endurance Training on Surgical Outcomes and Evaluation of Patient Compliance With Prehabilitation in Colorectal Surgery: A Randomized Controlled Trial”. Its implications have not yet been summarized in a source-checked review. Read update ↗ Explore research → | 6 collected reports AI review not yet available |