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Dates show original publication, separately from when we added the story. Clinical trials lists registry activity separately. Check collection coverage.

  5. Trial registry · no verified findings· The University of Texas Health Science Center at San Antonio

    Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly: Immune, Cognitive, and Functional Consequences ((Substudy E - RAPA cMRI With LGE)

    Published Sep 23, 2026Added 1moStart a discussionShare on XRapamycin

    Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

    Evidence assessment pending

    Read the source · The University of Texas Health Science Center at San Antonio ↗
  10. Trial registry · no verified findings· The University of Hong Kong

    The Effectiveness of an Elastic Band -Based Progressive Resistance Training (EB-PRT) in Improving Sarcopenia and Clinical Outcomes Among Patients With Heart Failure: A Pilot Mixed-method Study

    Published Sep 4, 2026Added 1moStart a discussionShare on XResistance training

    Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

    Evidence assessment pending

    Read the source · The University of Hong Kong ↗
  11. Trial registry · no verified findings· Federal University of Rio Grande do Sul

    Effects of a Multicomponent Exercise Program Based on the Vivifrail Protocol on Functional Capacity, Muscle Morphology, and Cognition in Nonagenarians: A Randomized Clinical Trial

    Published Sep 3, 2026Added 1moStart a discussionShare on XExercise

    Trial registry update: ENROLLING_BY_INVITATION. No results reported in the supplied registry record.

    Evidence assessment pending

    Read the source · Federal University of Rio Grande do Sul ↗
  20. Trial registry · no verified findings· University of Milano Bicocca

    Multidomain intervention feasibility study in older adults shows completion rates at 6-month follow-up.

    Published Sep 18, 2026Added 1moStart a discussionShare on XExerciseSocial connection

    FORMULA 100 is a prospective single-arm feasibility study of an ICOPE-based multidomain intervention in 250 community-dwelling adults aged 65+ at two Italian Active Ageing Centers. Participants were screened for intrinsic capacity decline, underwent multidimensional assessment, and received a personalized 3-month intervention addressing physical, cognitive, nutritional, psychological, sensory, and social needs. The primary outcome was the proportion completing 6-month follow-up; effect sizes on health outcomes were not reported.

    Evidence assessment pending

    Read the source · University of Milano Bicocca ↗
  24. Trial registry · no verified findings· Icahn School of Medicine at Mount Sinai

    A Phase 1b, Multi-cohort Clinical Trial Assessing Safety and Feasibility of Exercise and Spermidine Administered in Conjunction With Lamivudine (RTi) or Rapamycin (mTORi) to Assess Impact on Dynamic Changes of Inflammation and Aging

    Published Aug 27, 2026Added 1moStart a discussionShare on XExerciseSpermidine

    Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

    Evidence assessment pending

    Read the source · Icahn School of Medicine at Mount Sinai ↗
  25. Trial registry · no verified findings· Dr. Chris McGlory, PhD

    RCT of polyphenol supplementation combined with 12-week exercise in older adults tested feasibility and physical performance.

    Published Aug 27, 2026Added 1moStart a discussionShare on XResistance trainingExercise

    A randomized controlled pilot feasibility trial examined whether polyphenol supplementation combined with 12 weeks of supervised resistance and aerobic exercise could improve physical function and muscle health in older adults compared to placebo. Participants received either a polyphenol blend or maltodextrin placebo while completing the exercise program. The study included exploratory analysis of muscle biopsies and plasma samples to assess cellular and molecular effects.

    Evidence assessment pending

    Read the source · Dr. Chris McGlory, PhD ↗
  28. Trial registry · no verified findings· University Hospital, Akershus

    The Efficacy and Safety of a Mental Intervention Program vs. Usual Care and Nicotinamide Riboside (NR) vs. Placebo for Improving Health-related Quality of Life in Long Covid: A 2 x 2 Factorial Randomized Controlled Trial

    Published Aug 25, 2026Added 1moStart a discussionShare on XNicotinamide riboside

    Trial registry update: COMPLETED. No results reported in the supplied registry record.

    Evidence assessment pending

    Read the source · University Hospital, Akershus ↗