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  1. Trial registry · no verified findings· Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

    Dasatinib and Quercetin, a Combination of Senolytics to Treat Fibrotic Non-alcoholic Fatty Liver Disease - the TRUTH Study

    Published Apr 15, 2026Added 1moStart a discussionShare on XSenolytics

    Trial registry update: COMPLETED. No results reported in the supplied registry record.

    Evidence assessment pending · RCT

    Read the source · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) ↗
  2. Trial registry · no verified findings· Mayo Clinic

    Proposed RCT of fisetin on stem cell function and kidney outcomes in advanced chronic kidney disease

    Published Jan 28, 2026Added 1moStart a discussionShare on XStem cell therapy

    This is a proposed study protocol, not a completed trial. The researchers planned to examine whether fisetin would improve adipose tissue-derived mesenchymal stem/stromal cell function, kidney function, inflammation markers, and physical function in individuals with advanced chronic kidney disease. No results are reported because the study has not been conducted.

    Evidence assessment pending · RCT

    Read the source · Mayo Clinic ↗
  3. Trial registry · no verified findings· Diabetes Foundation, India

    The Effect of Metformin Treatment on Surrogate Markers of Ageing (Leukocyte Telomere Length and Telomerase Activity), Longevity Gene Expression (Sirtuin 1, p66Shc, p53, Andmammalian Target of Rapamycin ), in North Indian Individuals With the Prediabetes: A Randomized Control Trial

    Published Dec 24, 2025Added 1moStart a discussionShare on XMetformin

    Trial registry update: COMPLETED. No results reported in the supplied registry record.

    Evidence assessment pending · RCT

    Read the source · Diabetes Foundation, India ↗
  4. Trial registry · no verified findings· Second Affiliated Hospital, Zhejiang University, School of Medicine

    Assessing the Role of GLP-1 Receptor Agonist Semaglutide and Dual GLP-I/GIP Receptor Agonist Tirzepatide in Delaying Genetic Aging in Adult Obese Patients Using the iWatchAge Technology

    Published Dec 19, 2025Added 1moStart a discussionShare on XGLP-1 agonistsMetformin

    Trial registry update: RECRUITING. No results reported in the supplied registry record.

    Evidence assessment pending · RCT

    Read the source · Second Affiliated Hospital, Zhejiang University, School of Medicine ↗
  5. Trial registry · no verified findings· Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    Klotho levels associated with bone density in women with systemic sclerosis: observational cross-sectional study

    Published Mar 12, 2025Added 1moStart a discussionShare on XKlotho

    This observational cross-sectional study examined whether klotho and related cytokines are associated with bone mineral density and osteoimmunological markers in female patients aged 45-65 with systemic sclerosis, compared to age and gender-matched healthy controls. The study investigates whether these factors relate to the microvascular damage and fibrosis characteristic of systemic sclerosis. No effect sizes, sample sizes, or specific findings are reported in the abstract.

    Evidence assessment pending · OBSERVATIONAL

    Read the source · Fondazione Policlinico Universitario Agostino Gemelli IRCCS ↗