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- Trial registry · no verified findings· Brigham and Women's Hospital
FEAST and HOPE: Redox PSC Pilot Study in PSC
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Brigham and Women's Hospital ↗ - Trial registry · no verified findings· Sheba Medical Center
Evidence-Based Longevity Interventions and Targeted Engagement (E.L.I.T.E.)
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Sheba Medical Center ↗ - Trial registry · no verified findings· Oklahoma Medical Research Foundation
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · Oklahoma Medical Research Foundation ↗ - Trial registry · no verified findings· AgelessRx
A Pilot Randomized Controlled Study of Combinatorial Gerotherapeutics for Healthspan Improvement
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · AgelessRx ↗ - Trial registry · no verified findings· Diabetes Foundation, India
The Effect of Metformin Treatment on Surrogate Markers of Ageing (Leukocyte Telomere Length and Telomerase Activity), Longevity Gene Expression (Sirtuin 1, p66Shc, p53, Andmammalian Target of Rapamycin ), in North Indian Individuals With the Prediabetes: A Randomized Control Trial
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Diabetes Foundation, India ↗ - Trial registry · no verified findings· Second Affiliated Hospital, Zhejiang University, School of Medicine
Assessing the Role of GLP-1 Receptor Agonist Semaglutide and Dual GLP-I/GIP Receptor Agonist Tirzepatide in Delaying Genetic Aging in Adult Obese Patients Using the iWatchAge Technology
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Second Affiliated Hospital, Zhejiang University, School of Medicine ↗ - Trial registry · no verified findings· University of Utah
Metformin to Prevent Inactivity-induced Loss of Muscle Health During Aging
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · University of Utah ↗ - Trial registry · no verified findings· State University of New York at Buffalo
Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS): Randomized, Placebo-controlled Pilot Study.
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · State University of New York at Buffalo ↗ - Trial registry · no verified findings· AgelessRx
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation: A Randomized, Controlled Trial
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · AgelessRx ↗ - Trial registry · no verified findings· Fundación Instituto de Investigación Sanitaria de Navarra
Exploring the Anti-ageing Effects of Metformin in COPD
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Fundación Instituto de Investigación Sanitaria de Navarra ↗ - Trial registry · no verified findings· Xuanwu Hospital, Beijing
A Phase II Exploratory Clinical Study Investigating the Geroprotective Effect of Metformin in Middle-aged and Elderly People
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Xuanwu Hospital, Beijing ↗ - Trial registry · no verified findings· The University of Texas Health Science Center at San Antonio
Metformin and Vaccine Response in Older Adults
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · The University of Texas Health Science Center at San Antonio ↗ - Trial registry · no verified findings· Matthew Neal MD
Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Optimizing Surgical Outcomes at UPMC
Trial registry update: TERMINATED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · Matthew Neal MD ↗ - Trial registry · no verified findings· University of New Mexico
A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · University of New Mexico ↗ - Trial registry · no verified findings· University of California, San Francisco
METforMIN: Metformin Administration for the Minimization of Geographic Atrophy Progression in Patients With Age-related Macular Degeneration
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · University of California, San Francisco ↗ - Trial registry · no verified findings· Mayo Clinic
(MATE) Metformin and Aging Trial in the Elderly: A Pilot and Feasibility Study
Trial registry update: TERMINATED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · Mayo Clinic ↗ - Trial registry · no verified findings· Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Randomized Controlled Trial of Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano ↗ - Trial registry · no verified findings· Albert Einstein College of Medicine
Metformin in Longevity Study (MILES).
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · Albert Einstein College of Medicine ↗ - Trial registry · no verified findings· UConn Health
Vaccination Efficacy With Metformin in Older Adults: A Pilot Study
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · UConn Health ↗ - Trial registry · no verified findings· VA Office of Research and Development
Metformin and Muscle in Insulin-resistant Older Veterans
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · VA Office of Research and Development ↗ - Trial registry · no verified findings· Philip Kern
Novel Actions of Metformin to Augment Resistance Training Adaptations in Older Adults
Trial registry update: COMPLETED. Results are posted in the registry; assessment pending.
Evidence assessment pending
Read the source · Philip Kern ↗ - Trial registry · no verified findings· Indonesia University
Randomized-Controlled Trial of Metformin to Prevent Frailty in Pre-frail Elderly
Trial registry update: UNKNOWN. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Indonesia University ↗ - Trial registry · no verified findings· Xiang Guang-da
Chronic Metformin Treatment Induces a Dietary Restriction-like State in Overweight Human
Trial registry update: UNKNOWN. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Xiang Guang-da ↗ - Trial registry · no verified findings· Guy's and St Thomas' NHS Foundation Trust
METformin And Longevity (METAL): A Window of Opportunity Study Investigating Biological Effects of Metformin in Localised Prostate Cancer
Trial registry update: UNKNOWN. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · Guy's and St Thomas' NHS Foundation Trust ↗ - Trial registry · no verified findings· University of Padova
Effects of Metformin on Longevity Gene Expression and Inflammation and Prediabetic Individuals. A Placebo-controlled Trial
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Evidence assessment pending
Read the source · University of Padova ↗